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Catalog of Services

Patient sample requirements for the majority of reference lab services is 10cc of clotted blood and 7cc of anticoagulated blood. The reference lab will issue a preliminary report within 4 hours of receipt of the sample and most final reports will then be issued within 24 hours. However, more complex problems may require additional time for resolution.

Antibody Identification - Level I
Determination of antibody specificity.  Includes:

  • ABO/Rh determination
  • Antibody Detection
  • 2 panels
  • DAT
  • Appropriate antigen typing
  • Antibody Identification - Level II
    Determination of multiple or weakly reactive alloantibody specificity. Includes:

  • Level I workup
  • Select cells
  • Additional panel
  • Additional Antigen Typings
  • Antibody Identification Level III
    Determination of complex multiple or high frequency alloantibody specificity. Includes:

  • Level II workup
  • Rare cells and serum
  • Adsorbtions
  • Elutions
  • Titrations
  • Compatibility Test
    A procedure used to give an indication of blood group compatibility between donor and recipient.

  • Appropriate units of blood crossmatched on request
  • Investigation of Positive Direct Antiglobulin Test - Level I
    Determination of specificity of antibody coating the RBCs in vivo. Includes:

  • ABO/Rh determination
  • Antibody detection
  • Polyspecific,IgG C3 Coombs testing
  • Elution

    (autoimmune investigation requires 30cc of anticoagulated blood)
  • Investigation of Direct Antiglobulin Test - Level II
    Determination of specificity of antibody coating the RBCs in vivo, including investigation of drug induced hemolytic anemia. Includes:

  • Level I workup
  • Drug evaluation
  • Serum/Cell treatment
  • Red Cell separation
  • Identification of allo-antibodies

    (autoimmune investigation requires 30cc of anticoagulated blood)
  • Resolution of ABO Typing Discrepancies
    Confirmation of blood group. Discrepancies may result from intrinsic properties of serum or RBCs. Includes:

  • Forward type
  • Reverse type
  • Antibody detection/identification
  • Prenatal evaluation
    Screening procedure for the presence of alloantibody. Important for assessing possible risk from hemolytic disease of the newborn. Includes:

  • ABO/Rh determination
  • Antibody identification
  • DAT
  • Transfusion Reaction Investigation - Level I
    Serological investigation for immune mediated hemolysis Includes:

  • ABO/Rh determination
  • DAT
  • Antibody detection
  • Transfusion Reaction Investigation - Level II
    Serological investigation for immune mediated hemolysis Includes:

  • Level I workup
  • Antibody identification
  • Repeat crossmatches
  • Antigen typings
  • Evaluation of Fetal Maternal Hemmorhage
    Screening procedure for transplacental hemmorhage of Rho(D) negative patients. Positive results are quantified and RhIG dosage is determined.
    Cord Blood Evaluation
    Important for screening for hemolytic disease of the newborn. Includes:

  • ABO/Rh determination
  • DAT
  • Antibody detection/identification

    (testing requires a cord blood sample)
  • Antibody Titer
    Determination of natural antibody titers (isohemagglutinin titers), or monitoring presence of an IgG class alloantibody in the serum of an obstetrical patient. Includes:

  • ABO/Rh determination
  • Room temperature and AGT titers
  • Complete Cell Antigen Profile
    Determination of antigens present on an individual's RBCs. Includes:

  • Type for D, C, E, c, e, Cw, - M, N, S, s, - Lea, Leb, - Jka, Jkb, - Fya, Fyb, - K, k, P1
  • Antigen type
    Determination of requested antigen status of RBC.

  • Type for requested antigen
  • Lewis Secretor Status Determination
    Determination of Lewis secretory status. Includes:

  • Lewis red cell antigen typing
  • Investigation of Red Cell Polyagglutination
    Investigation of the condition in which red cells agglutinate in all sera. This abnormality may result from RBC surface modification by microbial enzymes, incomplete RBC membrane biosynthesis or rare genetic variants. Includes:

  • ABO/Rh determination
  • Antibody detection/identification
  • Polyagglutination testing
  • Donath-Landsteiner Test
    Assists in the diagnosis of paroxsysmal cold hemoglutinuria. Includes:

  • ABO/Rh determination
  • Antibody detection
  • DAT
  • Donath-Landstyeiner test
  • Sucrose Hemolysis Test
    Assists in the diagnosis of paroxsysmal nocturnal hemoglobinuria. Includes:

  • ABO/Rh determination
  • Antibody detection
  • DAT
  • Sucrose hemolysis test
  • Acid Hemolysis Test (HAMS Test)
    Assists in the diagnosis of paroxsysmal nocturnal hemoglobinuria. Includes:

  • ABO/Rh determination
  • Antibody detection
  • DAT
  • Acid hemolysis test
  • Chromium 51 Red Cell Survival
    Monitors the red blood cell survival rate of transfused cells.

     
     

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