Red Cell Reference Laboratory
Catalog of Services
| Patient sample requirements for the majority
of reference lab services is 10cc of clotted blood and 7cc of anticoagulated blood. The
reference lab will issue a preliminary report within 4 hours of receipt of the sample and
most final reports will then be issued within 24 hours. However, more complex
problems may require additional time for resolution. |
| Antibody Identification
- Level I Determination of antibody
specificity. Includes:
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Antibody Identification
- Level II Determination of multiple or
weakly reactive alloantibody specificity. Includes:
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| Antibody Identification
Level III Determination of complex multiple or high frequency alloantibody specificity. Includes:
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Compatibility Test A procedure used to give an indication of blood group compatibility between donor and recipient.
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| Investigation of
Positive Direct Antiglobulin Test - Level I Determination of specificity of antibody coating the RBCs in vivo. Includes:
(autoimmune investigation requires 30cc of anticoagulated blood) |
Investigation of Direct
Antiglobulin Test - Level II Determination of specificity of antibody coating the RBCs in vivo, including investigation of drug induced hemolytic anemia. Includes:
(autoimmune investigation requires 30cc of anticoagulated blood) |
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| Resolution of ABO Typing
Discrepancies Confirmation of blood group. Discrepancies may result from intrinsic properties of serum or RBCs. Includes:
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Prenatal evaluation Screening procedure for the presence of alloantibody. Important for assessing possible risk from hemolytic disease of the newborn. Includes:
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| Transfusion Reaction
Investigation - Level I Serological investigation for immune mediated hemolysis Includes:
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Transfusion Reaction
Investigation - Level II Serological investigation for immune mediated hemolysis Includes:
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| Evaluation of Fetal
Maternal Hemmorhage Screening procedure for transplacental hemmorhage of Rho(D) negative patients. Positive results are quantified and RhIG dosage is determined. |
Cord Blood Evaluation Important for screening for hemolytic disease of the newborn. Includes:
(testing requires a cord blood sample) |
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| Antibody Titer Determination of natural antibody titers (isohemagglutinin titers), or monitoring presence of an IgG class alloantibody in the serum of an obstetrical patient. Includes:
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Complete Cell Antigen
Profile Determination of antigens present on an individual's RBCs. Includes
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| Antigen type Determination of requested antigen status of RBC.
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Lewis Secretor Status
Determination Determination of Lewis secretory status. Includes:
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| Investigation of Red
Cell Polyagglutination Investigation of the condition in which red cells agglutinate in all sera. This abnormality may result from RBC surface modification by microbial enzymes, incomplete RBC membrane biosynthesis or rare genetic variants. Includes:
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Donath-Landsteiner Test Assists in the diagnosis of paroxsysmal cold hemoglutinuria. Includes:
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| Sucrose Hemolysis Test Assists in the diagnosis of paroxsysmal nocturnal hemoglobinuria. Includes:
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Acid Hemolysis Test
(HAMS Test) Assists in the diagnosis of paroxsysmal nocturnal hemoglobinuria. Includes:
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| Chromium 51 Red Cell
Survival Monitors the red blood cell survival rate of transfused cells. |
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Please contact the Central Blood Bank Red Cell Reference Lab at (412)209-7470 or email Beth Jochum at bjochum@itxm.org for more information or to request a requisition for ordering services. |
[ CTS ]
